Carrageenan/MIV-150 (PC-815), a combination microbicide.

@article{FernndezRomero2007CarrageenanMIV150A,
  title={Carrageenan/MIV-150 (PC-815), a combination microbicide.},
  author={Jos{\'e} A Fern{\'a}ndez-Romero and Mitchell Thorn and Stuart Grant Turville and Kanani E. Titchen and Kristin Sudol and Jifan Li and Todd F. Miller and Melissa Robbiani and Robin A. Maguire and R. W. Jun. Buckheit and Tracy L. Hartman and David Michael Phillips},
  journal={Sexually transmitted diseases},
  year={2007},
  volume={34 1},
  pages={
          9-14
        }
}
OBJECTIVE The objective of this article is to study the effect of PC-815, a novel combination microbicide containing carrageenan and the nonnucleoside reverse transcriptase inhibitor (NNRTI) MIV-150, in blocking HIV-1 and HIV-2 infections in vitro as compared with Carraguard alone. GOAL The goal of this study was to develop a combination microbicide that is more efficacious than Carraguard against HIV-1 and HIV-2. STUDY DESIGN The microtiter syncytial assay was used to evaluate: 1) the… CONTINUE READING
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