Carotid plaques, but not common carotid intima–media thickness, are independently associated with aortic stiffness

  title={Carotid plaques, but not common carotid intima–media thickness, are independently associated with aortic stiffness},
  author={Mahmoud Zureik and Mohammed Temmar and Chris Adamopoulos and J M Bureau and Dominique Courbon and Fr{\'e}d{\'e}rique Thomas and Kathryn E Bean and Pierre Jean Touboul and Pierre Ducimetiere and Athanase Benetos},
  journal={Journal of Hypertension},
Objective It has been suggested that non-invasive aortic stiffness measurements can be used as an indicator of atherosclerosis. The relationships of arterial stiffness with arterial wall hypertrophy and atherosclerosis however, have rarely been investigated in large-scale studies. The present study reports the associations of carotid arterial structure assessed by B-mode ultrasound with carotid-femoral pulse-wave velocity in hypertensive and non-hypertensive subjects. Design and methods Free… 
Echogenic Carotid Plaques Are Associated With Aortic Arterial Stiffness in Subjects With Subclinical Carotid Atherosclerosis
This study provides the first evidence that echogenic but not echolucent carotid plaques are associated with aortic arterial stiffness, and this association applies to individuals with normal blood pressure and those with elevated blood pressure.
Influence of carotid atherosclerotic plaques on pulse wave assessment with arterial tonometry
Measurement of PWV and of variables derived from the central pulse waveform analysis by carotid tonometry is not biased by the presence of local atherosclerotic plaques.
Arterial Stiffness Is Associated With Carotid Intraplaque Hemorrhage in the General Population: The Rotterdam Study
Higher PWV is associated with presence and composition of carotid atherosclerotic plaques, in particular with intraplaque hemorrhage, and these findings provide further clues for understanding the development of vulnerable atheosclerotic plaque.
The association between aortic arterial stiffness, carotid intima-media thickness and carotid plaques in community-dwelling older adults: A population-based study
This study shows an independent association between aPWV and cIMT but not with carotid plaques, which may indicate distinct phenotypes for atherosclerosis.
Relationship between carotid intima-media thickness and arterial stiffness in children after Kawasaki disease
The increased carotid IMT in children after Kawasaki disease is associated with systemic arterial stiffness, and significant determinants of carotID IMT were identified by multivariate analysis.
Aortic pulse wave velocity results depend on which carotid artery is used for the measurements
It was found that use of the right carotid artery provided significantly higher aPWV values when using different methods to estimate the travel length of the pulse wave, as right-side measurements provided higher values.
Femoral rather than carotid artery ultrasound imaging predicts extent and severity of coronary artery disease.
Femoral IMT is an independent predictor of a single-vessel disease, whereas femoral atherosclerotic plaque presence indicates advanced CAD.
Role of arterial stiffness in cardiovascular disease
PWV does not increase during early stages of atherosclerosis, but it does increase in the presence of aortic calcification that occurs within advanced atherosclerotic plaque, and the haemodynamic consequences of increased aorti stiffness are summarized.
Serum tissue inhibitors of metalloproteinases 1 (TIMP-1) and carotid atherosclerosis and aortic arterial stiffness
It is shown that there is a differential association of TIMP-1 with PWV, CCA-IMT and carotid plaques, and the results suggest that TIMp-1 might be involved in plaque formation.


Association Between Arterial Stiffness and Atherosclerosis: The Rotterdam Study
This population-based study shows that arterial stiffness is strongly associated with atherosclerosis at various sites in the vascular tree.
Common carotid intima-media thickness predicts occurrence of carotid atherosclerotic plaques: longitudinal results from the Aging Vascular Study (EVA) study.
4-year longitudinal study shows that CCA-IMT predicts carotid plaque occurrence in a large sample of relatively old subjects and suggests that increased intima-media thickness might occur in an earlier phase of the atherosclerotic process.
Viscoelastic properties of normal and atherosclerotic carotid arteries.
The carotid stiffness increases in areas with marked wall thickening and particularly in segments with plaque, which may increase the understanding of atherosclerotic progression and wall remodelling.
Arterial Enlargement in the Atherosclerosis Risk in Communities (ARIC) Cohort: In Vivo Quantification of Carotid Arterial Enlargement
Narrowing of the internal carotid artery lumen associated with thicker walls is consistent with the observation that stenosis develops in this region and often leads to symptoms.
Arterial stiffening and vascular calcifications in end-stage renal disease.
  • A. Guérin, G. London, S. Marchais, F. Métivier
  • Medicine, Biology
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2000
The presence of vascular calcifications in ESRD patients was associated with increased stiffness of large capacity, elastic-type arteries, like the aorta and CCA, and the extent of arterial calcifications increased with the use of calcium-based phosphate-binders.
Stiffness of systemic arteries in patients with myocardial infarction. A noninvasive method to predict severity of coronary atherosclerosis.
The static elastic properties of arterial tree (abdominal aorta and common carotid artery) provided sufficiently reliable information on changes caused by atherosclerosis.
Thickening of the carotid wall. A marker for atherosclerosis in the elderly? Cardiovascular Health Study Collaborative Research Group.
ECA IMT is associated with major risk factors for atherosclerosis and existing CHD and ASD in older adults, but this association is not as strong as that for ICA IMT.
Association of coronary disease with segment-specific intimal-medial thickening of the extracranial carotid artery.
These data support use of the mean aggregate extracranial carotid IMT for correlation with the status of coronary atherosclerosis; however, the data also support useof the mean common plus bifurcation, since there is little increase in predictive power of themean aggregate over this index.
Correlation of ultrasound-measured common carotid artery stiffness with pathological findings.
To quantitatively and noninvasively evaluate common carotid atherosclerosis in a series of patients, we measured the stiffness parameter beta, which represents the mechanical properties of the