Carotid body chemoreceptors as a pharmacological model

  title={Carotid body chemoreceptors as a pharmacological model},
  author={Daniel S. Mcqueen},
Abstract Carotid chemoreceptors provide a model for studying the actions of peptides and other substances in an isolated organ under controlled conditions using a variety of techniques, e.g. neuropharmacological, radioligand binding, immunocytochemical, biochemical and biophysical. It should be possible, for example, to determine whether chemodepression evoked by enkephalins results from changes in Ca 2+ uptake, and/or in cAMP levels, which in turn cause a reduction in transmitter release. As… CONTINUE READING


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