Carotenoids/vitamin C and smoking‐related bladder cancer

@article{Castelao2004CarotenoidsvitaminCA,
  title={Carotenoids/vitamin C and smoking‐related bladder cancer},
  author={Jos{\'e} Esteban Castelao and Jian-Min Yuan and Manuela Gago-Dom{\'i}nguez and Paul L. Skipper and Steven R Tannenbaum and Kenneth K. Chan and Mary A. Watson and Douglas A. Bell and Gerhard A. Coetzee and Ronald K. Ross and Mimi C. Yu},
  journal={International Journal of Cancer},
  year={2004},
  volume={110}
}
Previous epidemiological studies of fruit and vegetable intake and bladder cancer risk have yielded inconsistent results, especially with respect to the role of cigarette smoking as a possible modifier of the diet‐bladder cancer association. A population‐based case‐control study was conducted in nonAsians of Los Angeles, California, which included 1,592 bladder cancer patients and an equal number of neighborhood controls matched to the index cases by sex, date of birth (within 5 years) and race… 

Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition

The findings do not support an effect of fruit and vegetable consumption, combined or separately, on bladder cancer risk.

Dietary Intake of Vegetables and Fruits and the Modification Effects of GSTM1 and NAT2 Genotypes on Bladder Cancer Risk

The data strongly support that high vegetable consumption, especially cruciferous vegetable intake, may protect against bladder cancer and that genetic variants of GSTM1 and NAT2 may modify the association.

Intake of fruits and vegetables and polymorphisms in DNA repair genes in bladder cancer.

A reduced risk of bladder cancer was found associated with fruit and vegetable intake and the fruits and vegetables associated with decreased risks included leafy green vegetables, cruciferous vegetables, apples and citrus fruits.

Protective effects of plasma carotenoids on the risk of bladder cancer.

Minerals and vitamins and the risk of bladder cancer: results from the New Hampshire Study

The findings suggest further investigation of the effect of vitamin E, carotenoids, vitamin D, thiamin, niacin, and vitamin E on bladder cancer risk may be warranted, and future studies should focus on high risk groups such as heavy smokers and older individuals.

Dietary factors associated with bladder cancer

There is no strong evidence to suggest that supplementation with any common micronutrient is effective in reducing BC risk, but the observation that a diet rich in fruits and vegetables and low in processed meat along with especially smoking cessation may convey some protective effects against BC risk is upheld.

Dietary carotenoids and genetic instability modify bladder cancer risk.

Evidence of a preventive role for carotenoids in bladder cancer is provided, and these data may have important implications for cancer prevention, especially for individuals susceptible to DNA damage.

Fruit consumption reduces the effect of smoking on bladder cancer risk. The Belgian case control study on bladder cancer

It is concluded that fruit consumption may decrease the effect of smoking on developing bladder cancer andAntioxidants, found in fruit, may protect against the damage caused by free radicals found in cigarette smoke.

Dietary sources of N‐nitroso compounds and bladder cancer risk: Findings from the Los Angeles bladder cancer study

Results of this study are consistent with a role of dietary sources of NOC precursors from processed meats in bladder cancer risk, suggesting consumption of meats with high amine and heme content such as salami and liver as a risk factor for bladder cancer.
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