Carnosic Acid Suppresses the H2O2-Induced Mitochondria-Related Bioenergetics Disturbances and Redox Impairment in SH-SY5Y Cells: Role for Nrf2

@article{Oliveira2016CarnosicAS,
  title={Carnosic Acid Suppresses the H2O2-Induced Mitochondria-Related Bioenergetics Disturbances and Redox Impairment in SH-SY5Y Cells: Role for Nrf2},
  author={Marcos Roberto Oliveira and Gustavo Costa Ferreira and Alessandra Peres and Simone Morelo Dal Bosco},
  journal={Molecular Neurobiology},
  year={2016},
  volume={55},
  pages={968-979}
}
  • Marcos Roberto Oliveira, Gustavo Costa Ferreira, +1 author Simone Morelo Dal Bosco
  • Published in Molecular Neurobiology 2016
  • DOI:10.1007/s12035-016-0372-7
The phenolic diterpene carnosic acid (CA, C20H28O4) exerts antioxidant, anti-inflammatory, anti-apoptotic, and anti-cancer effects in mammalian cells. CA activates the nuclear factor erythroid 2-related factor 2 (Nrf2), among other signaling pathways, and restores cell viability in several in vitro and in vivo experimental models. We have previously reported that CA affords mitochondrial protection against various chemical challenges. However, it was not clear yet whether CA would prevent… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 103 REFERENCES

Oxidative stress and neurodegeneration: where are we now

B Halliwell
  • J Neurochem
  • 2006
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Epigallocatechin gallate and mitochondria-A story of life and death.

Marcos Roberto de Oliveira, Seyed Fazel Nabavi, Maria Daglia, Luca Rastrelli, Seyed Mohammad Nabavi
  • Pharmacological research
  • 2016

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