Carnitine partially protects the rat testis against the late damage produced by doxorubicin administered during pre‐puberty

@article{Cabral2014CarnitinePP,
  title={Carnitine partially protects the rat testis against the late damage produced by doxorubicin administered during pre‐puberty},
  author={R E L Cabral and Fatima Kazue Okada and Taiza Stumpp and Vanessa Vendramini and Sandra Maria Miraglia},
  journal={Andrology},
  year={2014},
  volume={2}
}
Doxorubicin, an anticancer drug, is widely included in chemotherapy protocols to combat childhood cancer. Carnitine, an important quaternary amine, is present in testis and epididymis and is involved in sperm maturation; it has been used in infertility treatment. In a previous study, our group observed that l‐carnitine given before etoposide, another chemotherapeutic drug, reduces the spermatogenic damage and protects germ cells against apoptosis. This study aimed to evaluate the antiapoptotic… 

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