Carnitine as a free radical scavenger in aging.

  title={Carnitine as a free radical scavenger in aging.},
  author={P J Arockia Rani and Chinnakkannu Panneerselvam},
  journal={Experimental gerontology},
  volume={36 10},
Carnitine (4-N-trimethylammonium-3-hydroxybutyric acid) plays an important role in the translocation of acetyl moieties from the mitochondria into the cytoplasm for acetylcholine synthesis in the brain. Previous studies in our laboratory have shown that L-carnitine suppresses oxidative damage during aging. This study was carried out to see the effect of L-carnitine on the status of non-enzymatic antioxidants and lipofuscin accumulation in various regions of the aged rat brain. We observed a… CONTINUE READING