Carnitine and deoxycarnitine concentration in rat tissues and urine after their administration.

@article{Sartorelli1989CarnitineAD,
  title={Carnitine and deoxycarnitine concentration in rat tissues and urine after their administration.},
  author={Lodovico Sartorelli and Giovanni Mantovani and M Ciman},
  journal={Biochimica et biophysica acta},
  year={1989},
  volume={1006 1},
  pages={15-8}
}
Administration of L-carnitine to rats was followed by an increase of deoxycarnitine in urine. Conversely, administration of deoxycarnitine caused an increase of carnitine. The latter treatment also produced a transient but significant diminution of L-carnitine in heart, skeletal muscle and kidney, but not in liver and plasma. Administration of D-carnitine to rats previously loaded with deoxycarnitine significantly depleted the elevated deoxycarnitine concentration in skeletal muscle and kidney… CONTINUE READING