Carney triad can be (rarely) associated with germline succinate dehydrogenase defects

@article{Boikos2016CarneyTC,
  title={Carney triad can be (rarely) associated with germline succinate dehydrogenase defects},
  author={Sosipatros Alexandros Boikos and Paraskevi Xekouki and Elena Fumagalli and Fabio Rueda Faucz and Margarita J Raygada and Eva Szarek and Evan R. Ball and S. Y. Kim and Markku Miettinen and Lee J Helman and J. Aidan Carney and Karel Pacak and Constantine A. Stratakis},
  journal={European Journal of Human Genetics},
  year={2016},
  volume={24},
  pages={569-573}
}
Carney triad, the association of paragangliomas/pheochromocytomas, gastrointestinal stromal tumors and pulmonary chondromas, is a sporadic condition that is significantly more frequent in females; its genetic etiology remains unknown. Carney triad is distinct from the dyad of paragangliomas/pheochromocytomas and gastrointestinal stromal tumors, known as Carney–Stratakis syndrome, which is inherited in an autosomal- dominant manner and is almost always caused by succinate dehydrogenase subunit… 

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Germline c.1A>C heterozygous pathogenic variant in SDHA reported for the first time in a young adult with a gastric gastrointestinal stromal tumour (GIST): a case report

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The Carney triad is a chronic, persistent, indolent but sometimes fatal disorder of unknown etiology.

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