Cargo proteins of plasma astrocyte‐derived exosomes in Alzheimer's disease

@article{Goetzl2016CargoPO,
  title={Cargo proteins of plasma astrocyte‐derived exosomes in Alzheimer's disease},
  author={Edward J. Goetzl and Maja Mustapic and Dimitrios Kapogiannis and Erez Eitan and Irina V. Lobach and Laura Goetzl and Janice B Schwartz and Bruce L Miller},
  journal={The FASEB Journal},
  year={2016},
  volume={30},
  pages={3853 - 3859}
}
Efficient intercellular transfer of RNAs, proteins, and lipids as protected exosomal cargo has been demonstrated in the CNS, but distinct physiologic and pathologic roles have not been well defined for this pathway. The capacity to isolate immunochemically human plasma neuron‐derived exosomes (NDEs), containing neuronspecific cargo, has permitted characterization of CNS‐derived exosomes in living humans. Constituents of the amyloid β‐peptide (Aβ)42‐generating system now are examined in 2… 

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...

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