Care in the use of ibuprofen as an antipyretic in children.

  title={Care in the use of ibuprofen as an antipyretic in children.},
  author={Nadeem E. Moghal and Sally A. Hulton and David V. Milford},
  journal={Clinical nephrology},
  volume={49 5},
Ibuprofen is being widely used as an antipyretic in children. Recent studies indicate that it is as efficacious and with no significant difference in side-effects when compared to paracetamol. We describe three cases that illustrate that renal complications can occur when ibuprofen is prescribed in the presence of intravascular volume depletion and/or pre-existing renal problems. We discuss the mode of action of ibuprofen and recommend that its use as an antiypretic in children should be… CONTINUE READING

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