Cardiovascular safety of non-steroidal anti-inflammatory drugs revisited.

@article{Walker2018CardiovascularSO,
  title={Cardiovascular safety of non-steroidal anti-inflammatory drugs revisited.},
  author={Chris Walker and Luigi Marzio Biasucci},
  journal={Postgraduate medicine},
  year={2018},
  volume={130 1},
  pages={55-71}
}
Non-steroidal anti-inflammatory drugs (NSAIDs) have been widely used to treat inflammatory pain for decades. More recently, newer NSAIDs were developed to target the inducible isoform of cyclooxygenase (COX), COX-2, with the aim of reducing gastrointestinal toxicity. While the COX-2 selective inhibitors were effective in reducing pain and gastrointestinal harm, they soon were associated with an increased risk of adverse cardiovascular events. Initially, the view emerged that selective… CONTINUE READING
2 Citations
155 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 155 references

Similar Papers

Loading similar papers…