Cardiovascular regulation during insulin infusion into the carotid or vertebral artery in dogs.

Abstract

OBJECTIVE To test the hypothesis that insulin increases heart rate and arterial pressure via direct effects on the central nervous system. METHODS AND DESIGN Insulin was infused into the cerebral circulation of conscious dogs (n = 8) chronically instrumented for continuous infusions and measurement of arterial pressure, cardiac output, heart rate and… (More)

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