Cardiovascular reflex responses to ischemia during occlusion of celiac and/or superior mesenteric arteries.

@article{Rendig1997CardiovascularRR,
  title={Cardiovascular reflex responses to ischemia during occlusion of celiac and/or superior mesenteric arteries.},
  author={Stephen V. Rendig and Premjit S Chahal and John C. Longhurst},
  journal={The American journal of physiology},
  year={1997},
  volume={272 2 Pt 2},
  pages={
          H791-6
        }
}
Global abdominal visceral ischemia leads to profound cardiovascular reflex adjustments. However, the separate contributions of the celiac artery and superior mesenteric artery (SMA) vascular beds to this reflex are unknown. Accordingly, we compared the effects of single and combined occlusions of these vessels on blood pressure (BP) in anesthetized cats. Tissue mass and pH of selected organs, regional blood gases, pH, and lactate also were measured as potential contributing factors. Occlusion… 
Reflex cardiovascular response to brief abdominal visceral ischemia is mediated in part by prostaglandins.
Prostaglandin concentrations are elevated in intestinal lymph during brief abdominal visceral ischemia, and exogenously applied prostaglandins can directly stimulate or sensitize ischemically
Reflex cardiovascular response to brief abdominal visceral ischemia is mediated in part by prostaglandins.
Prostaglandin concentrations are elevated in intestinal lymph during brief abdominal visceral ischemia, and exogenously applied prostaglandins can directly stimulate or sensitize ischemically
Splanchnic Vasoregulation During Mesenteric Ischemia and Reperfusion in Pigs
TLDR
It is concluded that reduced mesenteric perfusion impairs the HABR, which recovers only partially after reperfusion, and the distribution of the increased celiac trunk flow secondary to PV occlusion ranges from increased HABr and decreased non-hepatic blood flow to decreased hepatic arterial blood flow and increased non- hepaticBlood flow (an inverse steal).
Effects of systemic arterial hypoperfusion on splanchnic hemodynamics and hepatic arterial buffer response in pigs.
TLDR
During low systemic perfusion, the HABR is exhausted and hepatic function is impaired without signs of cellular damage.
Bradykinin BK2 receptors contribute to reflex cardiovascular responses during brief abdominal ischemia.
TLDR
Results indicate that the stimulation of BK2 receptors on visceral afferent nerves by BK is responsible, at least in part, for the reflex cardiovascular response during visceral ischemia.
Changes in regional blood flow and pCO2 gradients during isolated abdominal aortic blood flow reduction
TLDR
During isolated reduction in abdominal aortic blood flow there is no preferential distribution to any splanchnic vascular bed and changes in regional pCO2 gradients reflect consistently the associated blood blow changes.
Reflex pressor response to arterial phenylbiguanide: role of abdominal sympathetic visceral afferents.
  • L. Fu, J. Longhurst
  • Biology, Medicine
    American journal of physiology. Heart and circulatory physiology
  • 1998
TLDR
Data indicate that PBG administered into the LV usually, but not always, evokes a depressor response that is converted to a pressor response following cervical vagotomy, and intra-arterial PBG induces aPressor response by stimulating 5-HT3receptors largely associated with ischemically sensitive abdominal sympathetic afferents.
Reflex pressor response to arterial phenylbiguanide: role of abdominal sympathetic visceral afferents.
TLDR
Data indicate that PBG administered into the LV usually, but not always, evokes a depressor response that is converted to a pressor response following cervical vagotomy, and intra-arterial PBG induces aPressor response by stimulating 5-HT3 receptors largely associated with ischemically sensitive abdominal sympathetic afferents.
EFFECTS OF LOW ABDOMINAL BLOOD FLOW AND DOBUTAMINE ON BLOOD FLOW DISTRIBUTION AND ON THE HEPATIC ARTERIAL BUFFER RESPONSE IN ANAESTHETIZED PIGS
TLDR
The HABR was not abolished during sustained low abdominal blood flow despite substantially reduced hepatic arterial blood flow and was not modified by dobutamine.
Diagnostic value of arterial blood gas lactate concentration in the different forms of mesenteric ischemia
TLDR
Arterial blood gas lactate levels seem to show good diagnostic accuracy in diagnosing small bowel arterial and nonocclusive ischemia and poor accuracy indiagnosing secondary mesenteric ischemIA, small bowel venous ischemies and ischemic colitis.
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