Cardiovascular properties of yangambin, a lignan isolated from Brazilian plants.

@article{Tibirica2001CardiovascularPO,
  title={Cardiovascular properties of yangambin, a lignan isolated from Brazilian plants.},
  author={Eduardo Tibirica},
  journal={Cardiovascular drug reviews},
  year={2001},
  volume={19 4},
  pages={313-28}
}
Yangambin was initially selected from a number of lignans isolated from Brazilian plants for its ability to antagonize Platelet-Activating Factor (PAF, 1-O-hexadecyl-2-acetyl- sn-glyceryl-3-phosphorylcholine)-induced biological effects. Subsequently it was shown that, besides its antagonistic properties at PAF receptors, yangambin also prevents the cardiovascular collapse observed during anaphylactic and endotoxic/septic shocks, as well as the vascular and cardiac hyporesponsiveness to… CONTINUE READING

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