Cardiovascular ochronosis.

  title={Cardiovascular ochronosis.},
  author={Julia Gaines and G M Pai},
  journal={Archives of pathology & laboratory medicine},
  volume={111 10},
A 64-year-old man with alkaptonuric ochronosis required aortic valve replacement for severe aortic stenosis and single-vessel aortocoronary artery bypass grafting for a subtotally occluded obtuse marginal branch of the circumflex coronary artery. Operative findings included ochronosis of a partly calcified aortic valve and the aortic intima. The aortic valve and a punch biopsy specimen of the ascending aorta were removed at surgery and were studied with transmission electron microscopy and… CONTINUE READING


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