Cardiovascular manifestations of systemic lupus erythematosus.

  title={Cardiovascular manifestations of systemic lupus erythematosus.},
  author={N E Doherty and Robert Siegel},
  journal={American heart journal},
  volume={110 6},
SLE affects most aspects of cardiac function, and recent studies have reported increasing cardiovascular morbidity and mortality. Pathologically, SLE is characterized by a pancarditis involving pericardium, myocardium, endocardium, and coronary arteries. In autopsy series, pericarditis has been found in 43% to 100% (mean 62%, Table I), and myocarditis was found in 8% to 78% (mean 40%, Table II), but both have been underdiagnosed clinically. Libman-Sacks lesions have been noted in 25% to 100… CONTINUE READING


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