Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial.

@article{Patel2015CardiovascularEI,
  title={Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial.},
  author={Manesh R. Patel and Richard C. Becker and Daniel M. Wojdyla and H{\aa}kan U. Emanuelsson and William Robert Hiatt and Jay Horrow and Steen Elkj{\ae}r Husted and Kenneth W. Mahaffey and Philippe Gabriel Steg and Robert F. Storey and Lars Wallentin and Stefan Karl James},
  journal={European journal of preventive cardiology},
  year={2015},
  volume={22 6},
  pages={734-42}
}
AIMS To determine the effect of ticagrelor compared to clopidogrel in patients with peripheral artery disease (PAD) and acute coronary syndromes (ACS). METHODS AND RESULTS PLATO (n = 18,624) was a multicentre, double-blind, randomized trial in ACS, that showed a 16% reduction in cardiovascular death (CV-death), myocardial infarction (MI) and stroke with ticagrelor compared with clopidogrel, without significant increase in overall major bleeding. We performed a post-hoc analysis of… CONTINUE READING
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