Cardiovascular effects of toxic concentrations of theophylline in the dog.

@article{Curry1985CardiovascularEO,
  title={Cardiovascular effects of toxic concentrations of theophylline in the dog.},
  author={StevenC. Curry and Michael V Vance and Ralph K. Requa and Rodney B Armstead},
  journal={Annals of emergency medicine},
  year={1985},
  volume={14 6},
  pages={
          547-53
        }
}
A canine model of theophylline toxicity was used to study the cardiovascular effects seen in severe theophylline poisoning. Eight mongrel dogs were divided equally into two groups. The dogs were anesthetized with pentobarbital and paralyzed with pancuronium bromide. They were ventilated with 100% oxygen and underwent the placement of pulmonary arterial, central venous, femoral arterial, and peripheral venous lines. Group 1 animals received 5.6 mL/kg D5W intravenously (IV) over 20 minutes. Group… CONTINUE READING
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