Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma

@article{Volkow2003CardiovascularEO,
  title={Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma},
  author={Nora D. Volkow and Gene-Jack Wang and Joanna S. Fowler and Patricia E. Molina and Jean Logan and Samuel John Gatley and Andrew N. Gifford and Yu-Shin Ding and Christopher T Wong and Naomi R. Pappas and Wei Zhu and James M. Swanson},
  journal={Psychopharmacology},
  year={2003},
  volume={166},
  pages={264-270}
}
Rationale. The cardiovascular effects of psychostimulant drugs (methylphenidate, amphetamine, cocaine) have been mostly associated with their noradrenergic effects. However, there is some evidence that dopaminergic effects are involved in the cardiovascular actions of these drugs. Here, we evaluated this association in humans. Methods. Positron emission… CONTINUE READING