Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction.

@article{Loh1994CardiovascularEO,
  title={Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction.},
  author={Evan Loh and Jonathan S. Stamler and Joshua M Hare and Joseph Loscalzo and Wilson Steven Colucci},
  journal={Circulation},
  year={1994},
  volume={90 6},
  pages={2780-5}
}
BACKGROUND Pulmonary vascular resistance (PVR) is frequently elevated in patients with advanced heart failure. Nitric oxide (NO), which contributes to the activity of endothelium-derived relaxing factor, causes relaxation of pulmonary arteries and veins in vitro. Inhalation of NO gas causes pulmonary vasodilation in patients with primary and secondary forms of pulmonary hypertension. METHODS AND RESULTS To test the hypothesis that inhalation of NO gas lowers PVR in patients with heart failure… CONTINUE READING
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Nitric oxide is an effective pulmonary vasodilator in cardiac transplant candidates with pulmonary hypertension

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