Cardiovascular effects of human insular cortex stimulation

  title={Cardiovascular effects of human insular cortex stimulation},
  author={Stephen M. Oppenheimer and Adrian W. Gelb and John P. Girvin and Vladimir Hachinski},
  pages={1727 - 1727}
Recent investigations indicate a site of cardiac representation within the left insular cortex of the rat. Moreover, the results of lesion studies suggest left-sided insular dominance for sympathetic cardiovascular effects. It is unclear whether similar representation exists within the human insular cortex. Five epileptic patients underwent intraoperative insular stimulation prior to temporal lobectomy for seizure control. On stimulation of the left insular cortex, bradycardia and depressor… 

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