Cardiovascular effects of epinephrine during rewarming from hypothermia in an intact animal model.

  title={Cardiovascular effects of epinephrine during rewarming from hypothermia in an intact animal model.},
  author={T. Kondratiev and E. Myhre and O. Simonsen and T. Nymark and T. Tveita},
  journal={Journal of applied physiology},
  volume={100 2},
  • T. Kondratiev, E. Myhre, +2 authors T. Tveita
  • Published 2006
  • Medicine
  • Journal of applied physiology
  • Rewarming from accidental hypothermia is often complicated by "rewarming shock," characterized by low cardiac output (CO) and a sudden fall in peripheral arterial pressure. In this study, we tested whether epinephrine (Epi) is able to prevent rewarming shock when given intravenously during rewarming from experimental hypothermia in doses tested to elevate CO and induce vasodilation, or lack of vasodilation, during normothermia. A rat model designed for circulatory studies during experimental… CONTINUE READING
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