Cardiovascular effects of 14-deoxy-11,12-didehydroandrographolide and Andrographis paniculata extracts.

@article{Yoopan2007CardiovascularEO,
  title={Cardiovascular effects of 14-deoxy-11,12-didehydroandrographolide and Andrographis paniculata extracts.},
  author={Nattaporn Yoopan and Piengpen Thisoda and Nuchanart Rangkadilok and Somjed Sahasitiwat and Nanthanit Pholphana and Somsak Ruchirawat and Jutamaad Satayavivad},
  journal={Planta medica},
  year={2007},
  volume={73 6},
  pages={
          503-11
        }
}
Andrographis paniculata has been widely used as a traditional medicine for the treatment of common cold, diarrhea and hypertension. The three major active diterpenoids are andrographolide (AP1), 14-deoxy-11,12-didehydroandrographolide (AP3) and neoandrographolide (AP4). It has been reported that AP3 has hypotensive and vasorelaxation effects. However, there is only limited information on the cardiovascular effects of the other diterpenoids and crude extracts containing different levels of AP3… 

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