Cardiovascular effects of acetylcholine microinjection into the ventrolateral and dorsal periaqueductal gray of rats

@article{Deolindo2011CardiovascularEO,
  title={Cardiovascular effects of acetylcholine microinjection into the ventrolateral and dorsal periaqueductal gray of rats},
  author={Milena Vieira Deolindo and Gislaine Garcia Pelosi and Cristiane Busnardo and Leonardo Barbosa Moraes Resstel and Fernando Morgan de Aguiar Corr{\^e}a},
  journal={Brain Research},
  year={2011},
  volume={1371},
  pages={74-81}
}
In the present study, we describe the cardiovascular effects of local acetylcholine (Ach) microinjection into both the ventrolateral (vlPAG) and dorsal (dPAG) periaqueductal gray areas of anesthetized rats and the possible local receptors involved with these responses. Microinjection of Ach (9, 27, 45 or 81 nmol/50 nL) into the vlPAG caused dose-related depressor responses. These hypotensive responses were blocked by local pretreatment with increasing doses of the nonselective muscarinic… CONTINUE READING

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