Cardiovascular dysautonomia in de novo Parkinson's disease without orthostatic hypotension.

@article{Oka2011CardiovascularDI,
  title={Cardiovascular dysautonomia in de novo Parkinson's disease without orthostatic hypotension.},
  author={Hisayoshi Oka and Chizuko Toyoda and Makiko Yogo and Soichiro Mochio},
  journal={European journal of neurology},
  year={2011},
  volume={18 2},
  pages={286-92}
}
BACKGROUND Clinical symptoms of Parkinson's disease (PD) include not only motor distress, but also autonomic dysfunction. OBJECTIVE To study the characteristics of subclinical autonomic nervous dysfunction in de novo PD without orthostatic hypotension (OH). METHODS Autonomic nervous function including cardiac sympathetic gain was evaluated on the basis of cardiac radioiodinated metaiodobenzylguanidine (MIBG) uptake, the response to the Valsalva maneuver, and spectral analyses of the RR… CONTINUE READING
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