Cardiovascular disease in Down syndrome

  title={Cardiovascular disease in Down syndrome},
  author={P. Versacci and D. di Carlo and M. C. Digilio and B. Marino},
  journal={Current Opinion in Pediatrics},
  • P. Versacci, D. di Carlo, +1 author B. Marino
  • Published 2018
  • Medicine
  • Current Opinion in Pediatrics
  • Purpose of review In the last 40 years, with a better understanding of cardiac defects, and with the improved results of cardiac surgery, the life expectancy of persons with Down syndrome has significantly increased. This review article reports on advances in knowledge of cardiac defects and cardiovascular system of persons with trisomy 21. Recent findings New insights into the genetics of this syndrome have improved our understanding of the pathogenetic mechanisms of cardiac defects. Recent… CONTINUE READING
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