Cardiovascular disease and anaphylaxis.

  title={Cardiovascular disease and anaphylaxis.},
  author={Ulrich R Mueller},
  journal={Current opinion in allergy and clinical immunology},
  volume={7 4},
PURPOSE OF REVIEW In severe anaphylaxis, the cardiovascular system is often heavily involved. Preexisting cardiovascular disease may therefore influence the course of anaphylaxis in a negative way. RECENT FINDINGS Systemic mastocytosis and elevated baseline serum tryptase are associated with severe and fatal anaphylaxis to hymenoptera stings. This is due to an increased number of cardiac mast cells resulting in high concentrations of cardiotoxic mast cell mediators in cardiac tissue during… CONTINUE READING
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