Cardiovascular and thermoregulatory effects of inhaled PM-associated transition metals: a potential interaction between nickel and vanadium sulfate.

@article{Campen2001CardiovascularAT,
  title={Cardiovascular and thermoregulatory effects of inhaled PM-associated transition metals: a potential interaction between nickel and vanadium sulfate.},
  author={M. Campen and Julianne P Nolan and Mette C.J. Schladweiler and Urmila P Kodavanti and Paul A Evansky and Daniel L. Costa and William P. Watkinson},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2001},
  volume={64 2},
  pages={243-52}
}
Recent epidemiological studies have shown an association between daily morbidity and mortality and ambient particulate matter (PM) air pollution. It has been proposed that bioavailable metal constituents of PM are responsible for many of the reported adverse health effects. Studies of instilled residual oil fly ash (ROFA) demonstrated immediate and delayed responses, consisting of bradycardia, hypothermia, and arrhythmogenesis in conscious, unrestrained rats. Further investigation of instilled… CONTINUE READING

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