• DOI:10.1016/0306-3623(75)90009-9
Corpus ID: 84577774

Cardiovascular and respiratory effects of Gaboon viper venom

@article{Whaler1975CardiovascularAR,
  title={Cardiovascular and respiratory effects of Gaboon viper venom},
  author={B. Whaler},
  journal={General Pharmacology-the Vascular System},
  year={1975},
  volume={6},
  pages={35-41}
}

B. Whaler

Published 1975

Biology

General Pharmacology-the Vascular System

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Abstract 1. 1. Doses of venom (rabbit 0·7–2·7 mg/kg; monkey 0·20–0·33 mg/kg) given intravenously and killing in 20–200 min produce a marked and maintained fall in blood pressure. 2. 2. There is a progressive reduction in O 2 consumption accompanied in rabbits with hyperventilation and terminal pulmonary oedema. 3. 3. The heart is directly affected. 4. 4. Blood becomes incoagulable and there is also extensive internal haemorrhage, particularly in visceral tissues.