Cardiovascular alterations in septic shock.

Abstract

Cardiovascular alterations in sepsis include a decrease in vascular tone and an impairment in myocardial contractility, and occur largely as the result of the release and action of mediators of the sepsis cascade. Many mediators are involved including cytokines, particularly tumour necrosis factor and interleukin-1, and secondary mediators such as nitric… (More)

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