Cardiovascular Toxicity of Citrus aurantium in Exercised Rats

@article{Hansen2013CardiovascularTO,
  title={Cardiovascular Toxicity of Citrus aurantium in Exercised Rats},
  author={Deborah K. Hansen and Nysia I. George and Gene E. White and Ali Abdel-Rahman and Linda S. Pellicore and Daniel Fabricant},
  journal={Cardiovascular Toxicology},
  year={2013},
  volume={13},
  pages={208-219}
}
When safety concerns forced the removal of ephedra from the market, other botanicals, including Citrus aurantium or bitter orange (BO) were used as replacements. A major component of the BO extract is synephrine, a chemical that is structurally similar to ephedrine. Because ephedrine has cardiovascular effects that may be exacerbated during physical exercise, the purpose of this study was to determine whether extracts containing synephrine produced adverse effects on the cardiovascular system… CONTINUE READING
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Effect of constituents from Fructus aurantii 218 Cardiovasc Toxicol

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