Cardiovascular Response to Beta-Adrenergic Blockade or Activation in 23 Inbred Mouse Strains

Abstract

We report the characterisation of 27 cardiovascular-related traits in 23 inbred mouse strains. Mice were phenotyped either in response to chronic administration of a single dose of the beta-adrenergic receptor blocker atenolol or under a low and a high dose of the beta-agonist isoproterenol and compared to baseline condition. The robustness of our data is… (More)
DOI: 10.1371/journal.pone.0006610

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