Cardiovascular Adverse Effects of Antipsychotic Drugs

@article{Buckley2000CardiovascularAE,
  title={Cardiovascular Adverse Effects of Antipsychotic Drugs},
  author={N. Buckley and P. Sanders},
  journal={Drug Safety},
  year={2000},
  volume={23},
  pages={215-228}
}
Minor cardiovascular adverse effects from antipsychotic drugs are extremely common. They include effects such as postural hypotension and tachycardia due to anticholinergic or α1-adrenoceptor blockade, and may occur in the majority of patients at therapeutic dosages. There are a number of pharmacological effects that are of uncertain clinical significance, such as blockade of calmodulin, sodium and calcium channels and α2-adrenoceptors in the central nervous system. The most serious… Expand
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