Cardiotonic effect of Apocynum venetum L. extracts on isolated guinea pig atrium

@article{Irie2008CardiotonicEO,
  title={Cardiotonic effect of Apocynum venetum L. extracts on isolated guinea pig atrium},
  author={Kaoru Irie and Takahiro Sato and I. Tanaka and J. Nakajima and Maiko Kawaguchi and T. Himi},
  journal={Journal of Natural Medicines},
  year={2008},
  volume={63},
  pages={111-116}
}
  • Kaoru Irie, Takahiro Sato, +3 authors T. Himi
  • Published 2008
  • Chemistry, Medicine
  • Journal of Natural Medicines
  • The effects on guinea-pig heart muscle of extracts of Apocynum venetum L. leaf, root, stem, old stem and Venetron—a polyphenol-rich extract of leaves—were studied by recording the mechanical activity and heart rate of isolated right atria. Cymarin—a cardiac glycoside—was also determined in A. venetum extracts by LC–MS/MS analysis. All extracts examined here showed a weak cardiotonic effect, i.e., induced a contractile response of the isolated atria and increased the pulse at a concentration of… CONTINUE READING
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    References

    SHOWING 1-10 OF 13 REFERENCES
    [Studies on antihypertensive effect of Luobuma (Apocynum venetum L.) leaf extract (3)].
    • 17
    • PDF
    A NOVEL IN VITRO ENDOTHELIUM‐DEPENDENT VASCULAR RELAXANT EFFECT OF APOCYNUM VENETUM LEAF EXTRACT
    • 29
    Antidepressant effects of apocynum venetum leaves in a forced swimming test.
    • 85
    • PDF
    Anti-anxiety effects of Apocynum venetum L. in the elevated plus maze test.
    • 126
    Constituents from leaves of Apocynum venetum L.
    • 42
    Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents.
    • C. Lugnier
    • Biology, Medicine
    • Pharmacology & therapeutics
    • 2006
    • 748
    Human blood platelet 3': 5'-cyclic nucleotide phosphodiesterase. Isolation of low-Km and high-Km phosphodiesterase.
    • 121
    Chemical constituents of Apocynum venetum L. var basikurumon Hara
    • Takamine Kenkyusho Nenpo
    • 1957