Cardiopulmonary effects of hypercapnia during controlled intermittent positive pressure ventilation in the horse.

@article{Khanna1995CardiopulmonaryEO,
  title={Cardiopulmonary effects of hypercapnia during controlled intermittent positive pressure ventilation in the horse.},
  author={Ajay Khanna and W. N. Mcdonell and Doris H. Dyson and Patricia M. Taylor},
  journal={Canadian journal of veterinary research = Revue canadienne de recherche veterinaire},
  year={1995},
  volume={59 3},
  pages={213-21}
}
The cardiopulmonary effects of eucapnia (arterial CO2 tension [PaCO2] 40.4 +/- 2.9 mm Hg, mean +/- SD), mild hypercapnia (PaCO2, 59.1 +/- 3.5 mm Hg), moderate hypercapnia (PaCO2, 82.6 +/- 4.9 mm Hg), and severe hypercapnia (PaCO2, 110.3 +/- 12.2 mm Hg) were studied in 8 horses during isoflurane anesthesia with volume controlled intermittent positive pressure ventilation (IPPV) and neuromuscular blockade. The sequence of changes in PaCO2 was randomized. Mild hypercapnia produced bradycardia… CONTINUE READING