Cardiopulmonary effects and pharmacokinetics of i.v. dexmedetomidine in ponies.

  title={Cardiopulmonary effects and pharmacokinetics of i.v. dexmedetomidine in ponies.},
  author={R Bettschart-Wolfensberger and S L Freeman and I Mark Bowen and F Shojaee Aliabadi and Renate Weller and Mirja K Huhtinen and K W Clarke},
  journal={Equine veterinary journal},
  volume={37 1},
REASONS FOR PERFORMING STUDY Currently available sedatives depress cardiopulmonary function considerably; therefore, it is important to search for new, less depressive sedatives. The study was performed to assess duration and intensity of cardiopulmonary side effects of a new sedative, dexmedetomidine (DEX), in horses. OBJECTIVES To study pharmacokinetics and cardiopulmonary effects of i.v. DEX. METHODS Pharmacokinetics of 3.5 microg/kg bwt i.v. DEX were studied in a group of 8 mature (mean… CONTINUE READING


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