Cardiopulmonary bypass for surgical correction of congenital heart disease in children with sickle cell disease: a case series.

@article{Harban2008CardiopulmonaryBF,
  title={Cardiopulmonary bypass for surgical correction of congenital heart disease in children with sickle cell disease: a case series.},
  author={Fraser M Harban and Philip M. Connor and Robert E Crook and Robert Bingham},
  journal={Anaesthesia},
  year={2008},
  volume={63 6},
  pages={648-51}
}
We present a series of three children with sickle cell disease aged 3 months, 3 weeks and 18 months, all presenting for cardiac surgery requiring cardiopulmonary bypass. The cardiac lesions were atrioventricular septal defect, transposition of the great arteries and ventricular septal defect, with sickle cell loads of 35%, 11% and 39% respectively at presentation. We calculated that the bypass circuit would provide sufficient volume to decrease sickle cell levels to safe values, so we decided… CONTINUE READING