Cardioprotective effects of phosphocreatine on myocardial cell ultrastructure and calcium-sensing receptor expression in the acute period following high level spinal cord injury.

@article{Chen2014CardioprotectiveEO,
  title={Cardioprotective effects of phosphocreatine on myocardial cell ultrastructure and calcium-sensing receptor expression in the acute period following high level spinal cord injury.},
  author={Hui Chen and Chao Gong and Cheng Ma and Xiaoni Zhang and Lishuang Xu and Caizhu Lin},
  journal={Molecular medicine reports},
  year={2014},
  volume={10 1},
  pages={560-6}
}
Phosphocreatine (PCr) mobilizes high-energy phosphates in cardiac muscles, which is potentially useful as a cardioprotective agent in patients with spinal cord injury (SCI). The cardioprotective effects of PCr on myocardial cell ultrastructure and calcium-sensing receptor (CaSR) expression following high-level spinal cord injury (SCI) were investigated. Healthy adult male Sprague-Dawley (SD) rats (n=54) weighing 250-300 g were subjected to C7 SCI injury by Allen's method with or without… CONTINUE READING
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