Cardioprotective effects of incretin during ischaemia-reperfusion.

  title={Cardioprotective effects of incretin during ischaemia-reperfusion.},
  author={Kroekkiat Chinda and Siriporn C Chattipakorn and Nipon Chattipakorn},
  journal={Diabetes & vascular disease research},
  volume={9 4},
Incretin is a gut derived peptide hormone secreted in the intestine after food ingestion, and is degraded rapidly after secretion by dipeptidyl peptidase (DPP)-4. Incretin-based therapy, such as glucagon-like peptide (GLP)-1 and the DPP-4 inhibitor, has been proposed as a new therapeutic approach for the treatment of type 2 diabetic patients. In the past few years, growing evidence also demonstrated the cardioprotective effects of incretin-based therapy, especially during ischaemia-reperfusion… CONTINUE READING


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