Cardioprotective effects of fullerenol C(60)(Oh)(24) on a single dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm.

@article{Injac2008CardioprotectiveEO,
  title={Cardioprotective effects of fullerenol C(60)(Oh)(24) on a single dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm.},
  author={Rade M. Injac and M Per{\vs}e and Marija Bo{\vs}kovi{\'c} and Vukosava Djordjevic-Milic and Aleksandar N. Djordjevic and Asta Hvala and Anton Cerar and B. Strukelj},
  journal={Technology in cancer research & treatment},
  year={2008},
  volume={7 1},
  pages={15-25}
}
The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Sprague Dawley rats with chemically induced… CONTINUE READING