Cardioprotective effects of Nigella sativa oil on cyclosporine A-induced cardiotoxicity in rats.

@article{Ebru2008CardioprotectiveEO,
  title={Cardioprotective effects of Nigella sativa oil on cyclosporine A-induced cardiotoxicity in rats.},
  author={Uz Ebru and Uz Burak and Selcoki Yusuf and Bayrak Reyhan and Kaya Arif and Turgut H Faruk and Mete Emin and Karanfil Aydin and I Ihan Atilla and Sahin Semsettin and Erdemli Kemal},
  journal={Basic & clinical pharmacology & toxicology},
  year={2008},
  volume={103 6},
  pages={574-80}
}
Cyclosporine A is a well-known immunosuppressor agent universally used in allotransplantation. However, it has been demonstrated that this drug produces side-effects in several organs, particularly in the kidney and in the heart. Nigella sativa oil has long been used in folk medicine for a wide range of illnesses. One of the potential properties of N. sativa oil is the ability of one or more of its constituents to reduce toxicity due to its antioxidant activities. The antioxidant effects of N… CONTINUE READING
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