Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin gene.

@article{Zhuo2009CardioprotectiveEO,
  title={Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin gene.},
  author={Yang Zhuo and Pei-fang Chen and Ao-zhen Zhang and Han Zhong and Chen Chen and Yi-Zhun Zhu},
  journal={Biological & pharmaceutical bulletin},
  year={2009},
  volume={32 8},
  pages={1406-10}
}
Hydrogen sulfide (H(2)S), as an endogenous gas signaling molecule with important biological function that has been found recently, may play a protection in ischemic reperfusion (I/R) myocardium. We investigated the cardioprotective effect of H(2)S in rats model of ischemic reperfusion in vivo and a probably influence on the expression of survivin, an anti-apoptosis gene. Animals were randomly divided into 3 groups and received either vehicle, sodium hydrosulfide (NaHS) or DL-propargylglycine… CONTINUE READING

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