Cardioprotective Effects of Methanolic Extract of Scrophularia frigida on Ischemia-Reperfusion-Induced Injuries in Isolated Rat Heart

@article{Garjani2017CardioprotectiveEO,
  title={Cardioprotective Effects of Methanolic Extract of Scrophularia frigida on Ischemia-Reperfusion-Induced Injuries in Isolated Rat Heart},
  author={A. Garjani and H. Vaez and A. Delazar and Maryam Rameshrad and Fariba Heshmati Afshar and P. Asgharian},
  journal={Iranian Journal of Pharmaceutical Research : IJPR},
  year={2017},
  volume={16},
  pages={35 - 45}
}
Myocardial infarction is a common presentation of coronary artery disease and the leading cause of death worldwide. The present study investigated potential resistance to ischemia-reperfusion (I/R) injuries following administration of methanolic (MeOH) extract of Scrophularia frigida (S. frigida) in isolated rat heart. Male Wistar rat hearts (n= 8-10) were isolated and allowed to equilibrate for 20 min, and then subjected to 30 min regional ischemia followed by 120 min reperfusion. In the… Expand
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