Cardioprotective Effect of Ghrelin in Cardiopulmonary Bypass Involves a Reduction in Inflammatory Response

@inproceedings{Cao2013CardioprotectiveEO,
  title={Cardioprotective Effect of Ghrelin in Cardiopulmonary Bypass Involves a Reduction in Inflammatory Response},
  author={Yukun Cao and Jun Tang and Ting Yang and Heng Ma and Dinghua Yi and Chunhu Gu and Shiqiang Yu},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Ghrelin has been reported to protect the cardiovascular system; however, the cardioprotective effect of ghrelin against cardiopulmonary bypass (CPB) induced myocardial injury are unclear. In this study, the protective effect of ghrelin on CPB induced myocardial injury and the underlying mechanisms were investigated. METHODS AND RESULTS Adult male rats were subjected to CPB and randomly to receive vehicle (n = 8), ghrelin (n = 8), ghrelin plus [D-Lys3]-GHRP-6, a GHSR-1a inhibitor (n… CONTINUE READING
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