Cardiomyogenesis of embryonic stem cells upon purinergic receptor activation by ADP and ATP

Abstract

Purinergic signaling may be involved in embryonic development of the heart. In the present study, the effects of purinergic receptor stimulation on cardiomyogenesis of mouse embryonic stem (ES) cells were investigated. ADP or ATP increased the number of cardiac clusters and cardiac cells, as well as beating frequency. Cardiac-specific genes showed enhanced… (More)
DOI: 10.1007/s11302-015-9468-1

6 Figures and Tables

Topics

  • Presentations referencing similar topics