Cardiomyocyte transplantation improves heart function.

@article{Li1996CardiomyocyteTI,
  title={Cardiomyocyte transplantation improves heart function.},
  author={R. K.-Y. Li and Zhengping Jia and Richard D. Weisel and Donald A. G. Mickle and Jian-Ping Zhang and M K Mohabeer and Vivek Rao and Joan Ivanov},
  journal={The Annals of thoracic surgery},
  year={1996},
  volume={62 3},
  pages={654-60; discussion 660-1}
}
BACKGROUND Transplantation of cultured cardiomyocytes into myocardial scar tissue may prevent heart failure. METHODS Scar tissue was produced in the left ventricular free wall of 15 rats (weight, 450 g) by cryoinjury. Seven animals had operation only and survived for 8 weeks (sham group). Four weeks after cryoinjury, cultured fetal rat cardiomyocytes or culture medium was injected into the scar tissue of transplantation (n = 5) and control (n = 5) animals, respectively. Five other rats were… CONTINUE READING

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