Cardiomyocyte differentiation of human induced pluripotent stem cells.

@article{Zwi2009CardiomyocyteDO,
  title={Cardiomyocyte differentiation of human induced pluripotent stem cells.},
  author={Limor Zwi and Oren Caspi and Gil Arbel and Irit Huber and Amira Gepstein and In-Hyun Park and Lior Gepstein},
  journal={Circulation},
  year={2009},
  volume={120 15},
  pages={1513-23}
}
BACKGROUND The ability to derive human induced pluripotent stem (hiPS) cell lines by reprogramming of adult fibroblasts with a set of transcription factors offers unique opportunities for basic and translational cardiovascular research. In the present study, we aimed to characterize the cardiomyocyte differentiation potential of hiPS cells and to study the molecular, structural, and functional properties of the generated hiPS-derived cardiomyocytes. METHODS AND RESULTS Cardiomyocyte… CONTINUE READING