Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis.

@article{Schug2009CardiolipinAA,
  title={Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis.},
  author={Zachary T Schug and Eyal Gottlieb},
  journal={Biochimica et biophysica acta},
  year={2009},
  volume={1788 10},
  pages={2022-31}
}
Cardiolipin (CL) is a unique anionic phospholipid specific to the mitochondria. CL influences the activity of electron transport chain enzyme complexes as well as members of the Bcl-2 family. Interactions between Bcl-2 family members and other pro-apoptotic enzymes have been shown to be crucial for the transduction of the apoptotic signalling cascades… CONTINUE READING