Cardio protective effect of Coriandrum sativum L. on isoproterenol induced myocardial necrosis in rats.

@article{Patel2012CardioPE,
  title={Cardio protective effect of Coriandrum sativum L. on isoproterenol induced myocardial necrosis in rats.},
  author={Dipak K. Patel and Swati N. Desai and Hardik P Gandhi and Ranjitsinh V Devkar and A. V. Ramachandran},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2012},
  volume={50 9},
  pages={
          3120-5
        }
}
The preventive effect of Coriandrum sativum L. (CS) on cardiac damage was evaluated by Isoproterenol (IP) induced cardiotoxicity model in male Wistar rats. Rats were pretreated with methanolic extract of CS seeds at a dose of 100, 200 or 300 mg/kg orally for 30 days and they were subsequently administered (s.c.) with IP (85 mg/kg body weight) for the last two days. IP treated rats showed increased LPO, decreased levels of endogenous antioxidants and ATPases in the cardiac tissue together with… CONTINUE READING

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